Makoto Arita Selected Research

Phospholipases (Phospholipase)

1/2022	The interaction of secreted phospholipase A2-IIA with the microbiota alters its lipidome and promotes inflammation.
1/2017	PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis.

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Makoto Arita Research Topics

Disease

50	Inflammation (Inflammations) 10/2023 - 04/2003
15	Peritonitis 12/2014 - 05/2003
10	Neoplasms (Cancer) 12/2023 - 05/2013
7	Contact Dermatitis (Eczema, Contact) 01/2022 - 06/2013
7	Asthma (Bronchial Asthma) 01/2021 - 02/2013
6	Hypersensitivity (Allergy) 01/2020 - 01/2015
5	Dermatitis 01/2023 - 01/2018
5	Colitis 01/2023 - 05/2005
4	Fibrosis (Cirrhosis) 01/2023 - 07/2014
4	Rhinosinusitis 01/2021 - 01/2019
4	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2014
4	Obesity 12/2020 - 12/2010
3	Cardiovascular Diseases (Cardiovascular Disease) 12/2023 - 03/2005
3	Infections 04/2014 - 12/2005
2	Bacterial Infections (Bacterial Infection) 10/2023 - 01/2022
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 09/2023 - 03/2014
2	Insulin Resistance 09/2023 - 12/2010
2	Necrosis 01/2023 - 08/2015
2	Atopic Dermatitis (Atopic Eczema) 01/2023 - 01/2021
2	Non-alcoholic Fatty Liver Disease 01/2023 - 01/2017
2	Reperfusion Injury 12/2022 - 09/2003
2	Cysts 01/2022 - 01/2021
2	Alzheimer Disease (Alzheimer's Disease) 06/2021 - 05/2013
2	Pneumonia (Pneumonitis) 01/2021 - 01/2010
2	Nasal Polyps (Nasal Polyp) 01/2020 - 01/2019
2	Atherosclerosis 01/2019 - 01/2011
2	Atherosclerotic Plaque (Atheroma) 01/2019 - 11/2014
2	Disease Progression 01/2019 - 05/2013
2	Hypertrophy 01/2017 - 09/2014
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2015 - 01/2010
1	Kidney Diseases (Kidney Disease) 04/2024
1	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2023
1	Communicable Diseases (Infectious Diseases) 12/2023
1	Gaucher Disease (Gaucher's Disease) 12/2023
1	Ischemia 12/2023
1	Immune System Diseases (Immune Disorders) 01/2023
1	Vision Disorders (Hemeralopia) 01/2023
1	Fatty Liver 01/2023

Drug/Important Bio-Agent (IBA)

36	LipidsIBA 12/2023 - 05/2003
18	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2023 - 09/2007
18	Eicosapentaenoic AcidIBA 01/2022 - 03/2005
12	5S,12R,18R- trihydroxy- 6Z,8E,10E,14Z,16E- eicosapentaenoic acidIBA 10/2015 - 03/2005
10	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 03/2005
9	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2023 - 12/2010
9	ZymosanIBA 12/2014 - 08/2006
7	Docosahexaenoic AcidsIBA 01/2023 - 09/2009
7	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 10/2020 - 05/2003
6	CytokinesIBA 09/2023 - 08/2009
6	LipoxinsIBA 10/2012 - 05/2003
5	Proteins (Proteins, Gene)FDA Link 01/2023 - 05/2003
4	Dextran SulfateIBA 01/2023 - 01/2010
4	Dinoprostone (PGE2)FDA Link 01/2022 - 04/2003
4	Arachidonic Acid (Vitamin F)IBA 01/2019 - 09/2007
3	EnzymesIBA 04/2024 - 06/2013
3	Anti-Bacterial Agents (Antibiotics)IBA 10/2023 - 04/2014
3	Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA 01/2021 - 01/2013
3	Anti-Allergic Agents (Antiallergic Agents)IBA 11/2019 - 06/2015
3	17,18-epoxy-5,8,11,14-eicosatetraenoic acidIBA 01/2018 - 02/2014
3	EicosanoidsIBA 11/2017 - 05/2013
3	AcidsIBA 08/2015 - 01/2010
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2015 - 05/2005
3	lipoxin A4IBA 09/2014 - 02/2010
3	protectin D1IBA 03/2013 - 06/2007
2	CarbohydratesIBA 09/2023 - 01/2023
2	Insulin (Novolin)FDA Link 09/2023 - 12/2010
2	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2021
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2023 - 01/2018
2	AutacoidsIBA 01/2023 - 09/2005
2	CeramidesIBA 01/2023 - 01/2021
2	HaptensIBA 01/2022 - 06/2013
2	ChemokinesIBA 01/2022 - 01/2016
2	Secretory Phospholipases A2IBA 01/2022 - 06/2013
2	Phospholipases (Phospholipase)IBA 01/2022 - 01/2017
2	Amyloid (Amyloid Fibrils)IBA 06/2021 - 05/2013
2	Matrix Metalloproteinases (MMPs)IBA 06/2021 - 01/2014
2	Prostaglandin D2IBA 05/2021 - 05/2013
2	InterleukinsIBA 01/2021 - 03/2005
2	Phospholipids (Phosphatides)FDA LinkGeneric 01/2021 - 11/2017
2	Interleukin-17 (Interleukin 17)IBA 01/2021 - 01/2018
2	CholesterolIBA 01/2021 - 11/2014
2	LigandsIBA 01/2019 - 01/2010
2	Leukotriene B4IBA 01/2018 - 04/2003
2	Fish OilsIBA 01/2015 - 03/2005
2	SteroidsIBA 01/2015 - 09/2014
2	Interleukin-12 (IL 12)IBA 05/2005 - 03/2005
1	GlycolipidsIBA 04/2024
1	alkylglycerone-phosphate synthaseIBA 04/2024
1	GalactosyltransferasesIBA 04/2024
1	Uridine Diphosphate (UDP)IBA 04/2024
1	hexadecanal dehydrogenase (acylating) (fatty acyl-CoA reductase)IBA 04/2024
1	Glucosylceramidase (Glucocerebrosidase)IBA 12/2023
1	Glucosylceramides (Glucocerebrosides)IBA 12/2023
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2023
1	gluconic acid (gluconate)FDA LinkGeneric 10/2023
1	SolutionsIBA 10/2023
1	MonosaccharidesIBA 09/2023
1	7,14- dihydroxydocosa- 4,8,10,12,16,19- hexaenoic acidIBA 01/2023
1	resolvin D1IBA 01/2023

Therapy/Procedure

8	Therapeutics 12/2023 - 09/2005
2	Intravenous Injections 12/2018 - 11/2014